A limited number of genes, including Cu/Zn superoxide dismutase (SOD1), fused in sarcoma/translocated in liposarcoma (FUS/TLS or FUS), transactive response DNA binding protein 43 kDa (TDP-43), and chromosome 9 open reading frame 72 (C9ORF72), are responsible for a significant percentage of both familial (FALS) and sporadic ALS (SALS) cases [2,3,4]. Here, SOD1 is linked to liposarcoma.