INS and Hyperglycemia: The effect of baicalein on glucose uptake and insulin sensitivity to prevent hyperglycemia was investigated by Singh and Kakkar [34] who reported that 50% aqueous ethanolic O. indicum stem bark which contained baicalein showed anti-hyperglycemia effects in vitro (3T3-L1 adipocytes cell line) and in vivo (diabetic rat models) via the inhibition of α-glucosidase activity.