ITGB3 and Glanzmann thrombasthenia 1: Pathogenic variants in ITGA2B and ITGB3, the genes coding for the αIIb and β3, give rise to Glanzmann ́s Thrombasthenia (GT), a rare autosomal recessive (AR) bleeding disorder due to quantitative or qualitative defects of integrin αIIbβ3, characterized by absent PLT aggregation, and normal PLT counts and volumes [12].