IL1B and Stroke: However, 9 of 18 animals in the each of the vehicle and 1.5 mg/kg neflamapimod groups and 6 of 18 animals in the 4.5 mg/kg neflamapimod group had quantifiable IL-1β levels above 20 pg/mL in the injured right brain hemisphere, indicating that despite being six weeks from acute the stroke there was still detectable residual inflammation in a substantial percentage of the animals.