APL-KO mice showed increased LVDd, left ventricular end-diastolic volume (LVEDV), left ventricular end-systolic volume (LVESV) and decreased FS after MI compared with WT mice, whereas there were no significant differences in LVDd, LVEDV, LVESV and FS between WT and APL-KO mice after sham operation (Fig 1A, Table 2). Here, FASLG is linked to myocardial infarction.