In addition, we found that the expression of stemness genes was upregulated in the soft tumor cells (Nestin, OCT3/4 and SOX2 for 4T1/MCF‐7; Nanog, OCT3/4, SOX2, and CD133 for B16F1/MP‐1), while the BCL9L knockout reversed this effect (Fig EV5G). This evidence concerns the gene NES and neoplasm.