ALDOC and melanoma: In order to establish whether or not ALDOC plays a role in shaping the malignant phenotype of melanoma cells, we overexpressed or knocked‐down ALDOC expression in three different melanoma brain metastatic (MBM) variants (YDFR.CB3, M12.CB3, and DP.CB2), all of which overexpressed ALDOC following exposure to microglia‐derived factors.