STRING identified Adherens junction (hsa04520) with a subnetwork centered by CDC42 and ACTB (ACTB, CDC42, FYN, IGF1R, IQGAP1, PTPRJ, and TGFBR1) (Fig. 3C upper left), Lysine degradation (hsa00310: ASH1L, KMT2D, SETD7, and SUV420H1) (Fig. 3C lower right), and Transcriptional misregulation in cancer (hsa05202: CCND2, ELK4, EWSR1, IGF1R, SIN3A, amd TCF3). The gene discussed is ACTB; the disease is cancer.