Various blood-born host biomarkers of immunity and inflammation have been studied for their predictive and prognostic powers in gliomas, including the GBM: C-reactive protein, albumin, platelets, monocytes, neutrophils, lymphocytes, neutrophil to lymphocyte ratio (NLR), platelet to lymphocyte ratio (PLR), lymphocyte to monocyte ratio (LMR), prognostic nutritional index (PNI), Glasgow prognostic score (GPS), and lately, the systemic immune inflammation index (SII) and C-reactive protein to albumin ratio [9–16]. This evidence concerns the gene CRP and glioblastoma.