In particular, PAD patients displayed at the basal state a higher CD64 expression on PMN and a higher CD16 expression on monocytes, compared to healthy controls, despite the absence of an acute infection, as it was confirmed by CRP levels that were into normal range for the majority of patients (with an exception of a slight increase in some patients with CRD). The gene discussed is FCGR3B; the disease is peripheral arterial disease.