IKZF1 and pancytopenia due to IKZF1 mutations: As mentioned above, this patient carried a IKZF1 (Ikaros) mutation, and as it has been demonstrated by previous studies, CVID13 patients (carrying Ikaros mutations) show decreased percentages of CD16+ monocytes, as well as a defective dendritic cell maturation, affecting to a lesser degree the PMN maturation and function [44].