NTN1 and brain infarction: The results showed that the percentage of cerebral infarction volume in the cerebral hemispheres of the MCAO+Netrin-1 group was significantly higher than that of the MCAO group and the NS group, and the difference was statistically significant (P < 0.05), which was similar to the results of Huang et al. [14], indicating that Netrin-1 can effectively reduce the area of cerebral infarction in rats and improve brain tissue damage.