SOD1 and infection: Thus, the results of this study demonstrated that recombinant influenza virus subtype A/H5N1 expressing the Brucella L7/L12 or Omp16 or Omp19 or Cu-Zn SOD (SOD) proteins from the open reading frame (ORF) of the NS1 gene in combination with tetravalent formulations is a safe vector, and its protectiveness against B. melitensis 16М infection in the prime-boost regimen is comparable to the B. melitensis Rev.1 commercial vaccine in mouse and guinea pig models.