Although there were statistically significant differences between both groups as the uncontrolled arm had a higher rate of hypertension and dyslipidaemia, there was however no difference in the level of control of these two risk factors, the facts that the uncontrolled group had a higher rate of use of medication, especially insulin, would suggest the heightened efforts to control DM or might reflect advanced DM. This evidence concerns the gene INS and diabetes mellitus.