As shown in Figure 2(a), high expression of CBX3 in univariate analysis correlated with shorter overall survival times in patients with malignant tumors (HR = 1.81, 95% CI 1.46-2.25, P < 0.00001) and had the same result in multivariate analysis (HR = 1.95, 95% CI 1.63-2.34, P < 0.00001) (Figure 2(b)). This evidence concerns the gene CBX3 and cancer.