PTGS2 and rheumatoid arthritis: Quantitative TaqMan®-PCR investigation showed that mPGES-1 (Figure 2(a)) and COX-2 (Figure 3(a)) specific mRNA was significantly higher in synovial tissue of JT, OA, and RA patients compared to controls (P < 0.05; one-way ANOVA followed by Tukey's test); however, it was most prominent in RA synovium.