LAMB3 and toxoplasmosis: Moreover, based on the 51 common supertargets of the cohort and personalized approach (Fig. S6C) the down-regulated genes HLA-DRA and HLA-DRB1 were found to be prominently involved in all seven highlighted pathways, while the up-regulated gene LAMB3 (Fig. S3A) played an additional role in toxoplasmosis.