Possible associations are being explored between VDR gene variation and the development of different types of cancers (ApaI polymorphism in the VDR gene may prove to be a good marker for the use of individualized chemotherapy in the treatment of non-small cell lung carcinoma)8, autoimmune diseases (risk of developing multiple sclerosis is still being investigated)9, diabetes10,11, asthma12, cardiovascular diseases13, osteoporosis14, and susceptibility to infection15. The gene discussed is VDR; the disease is multiple sclerosis.