Possible associations are being explored between VDR gene variation and the development of different types of cancers (ApaI polymorphism in the VDR gene may prove to be a good marker for the use of individualized chemotherapy in the treatment of non-small cell lung carcinoma)8, autoimmune diseases (risk of developing multiple sclerosis is still being investigated)9, diabetes10,11, asthma12, cardiovascular diseases13, osteoporosis14, and susceptibility to infection15. This evidence concerns the gene VDR and autoimmune disease.