The N2 type has a high level of arginase 1 (arginase1, ARG1), which can induce the production of N0 enzymes, which inhibit the cell activity CD8T antitumor and promote the development of tumor;18 Another mechanism is related to the T lymphocytes, which have more types and functions and play a major role in inflammatory response. The gene discussed is ARG1; the disease is neoplasm.