Interestingly, survClust identified a small IDH-mutant subtype characterized by CDKN2A deletion (c4) that showed markedly worse survival among the IDH-mutant tumors, similar to the IDH-WT group (c5) that tends to behave far more aggressively with prognosis similar to glioblastomas. The gene discussed is CDKN2A; the disease is glioblastoma.