CSPG4 and epilepsy: While the exact purpose of NG2 cell activity in the formation of the glial scar remains unclear, increased expression, or deposits of NG2, otherwise known as chondroitin sulfate proteoglycan 4 (CSPG4), may form a barrier to repair damage in epilepsy-inducing lesions and significantly alter the function of surviving neurons and astrocytes, contributing to epileptogenesis [18].