The significantly enriched KEGG pathways are IL-17 signaling pathway, ErbB signaling pathway, colorectal cancer, MAPK signaling pathway, TNF signaling pathway, osteoclast differentiation, fluid shear stress and atherosclerosis, WNT signaling pathway, Hepatitis B and Kaposi sarcoma-associated herpesvirus infection. The gene discussed is EGFR; the disease is atherosclerosis.