Alzheimer’s disease (AD) is an age-associated dementia disorder characterized by the accumulation of extracellular amyloid-beta (Aβ) peptides in the senile plaques and by the hyperphosphorylation of tau (pTau) protein, leading to intracellular protein aggregation into bundles or filaments that are deposited as neurofibrillary tangles [6,7,8]. This evidence concerns the gene MAPT and Alzheimer disease.