The cardiac damage has been highlighted by several markers: inflammation (i.e., pericardial edema, Figure 2a), “defense mechanism” (i.e., cardiac hypertrophy) (Figure 2c–e), rhythm disturbances with likely conduction system damage (i.e., decrease in heart rate) (Figure 2b), hormonal reaction (i.e., increase of ANP and BNP) (Figure 3) and vascular endothelium damage (Figure 4). Here, NPPA is linked to cardiac hypertrophy.