The subgroup meta-analysis of the incidence rate of death from any cause in ischemic stroke or TIA aspirin non-responders with ATM versus those without ATM, using a fixed effects model because of low heterogeneity, indicated an effect size of 0.29 without statistical significance (OR 1.17; 95% CI 0.41 to 3.35) (Figure 7). This evidence concerns the gene ATM and ischemic stroke.