In this sense, while high BNP levels are associated with a worse prognosis in the general population [25] and in individuals with SCAD [30] or with a history of heart failure [26,31], the data on the association between CRP and cardiovascular disease are conflicting [32,33,34], likely because of the dependence of CRP on traditional CVR factors [35]. Here, NPPB is linked to cardiovascular disorder.