Further relevant effects of miR-8066 are related to the induction of the cytokine storm that may be observed in severely ill patients with COVID-19; the miRNA not only targets genes responsible for cytokine regulation [11] but its sequence also includes a core motif correlated with an increased probability of TLR-8 (toll-like receptor 8) expression via NF-κB, which leads to cytokine synthesis [57]. Here, TLR8 is linked to COVID-19.