ACE2 and severe acute respiratory syndrome: A study conducted by Mallick et al. [48] in 2009 evaluated the miRNA landscape in human bronchoalveolar stem cells (BASCs) during SARS-CoV infection, showing the upregulation of miR-17*, miR-574-5p, and miR-214, which repress virus replication and contribute to immune evasion until a successful transmission of the virus has taken place, as well as the downregulation of miR-223 and miR-98, which serves the regulation of BASC differentiation, activation of proinflammatory cytokines, and ACE2 suppression [48].