TARDBP and frontotemporal dementia: Known pathogenic mutations (e.g., C9ORF72 (Renton et al, 2011; DeJesus‐Hernandez et al, 2011), TARDBP (Van Deerlin et al, 2008), FUS (Vance et al, 2009), NEK1 (Kenna et al, 2016), SOD1 (Rosen et al, 1993)) have been identified in many familial cases and in 5–7% of non‐familial cases (Umoh et al, 2016); in addition, GWAS have revealed many loci of common genetic variation that confer risk for ALS and FTD.