Among these pathways, the hsa04151: PI3K-Akt signaling pathway, hsa04010: MAPK signaling pathway, hsa04350: TGF-β signaling pathway, hsa04370: VEGF signaling pathway, hsa04012: ErbB signaling pathway, and hsa04115: p53 signaling pathway correlated with tumorigenesis and pathogenesis of pancreatic cancer (Supplementary Figure S5). Here, TGFB1 is linked to familial pancreatic carcinoma.