BDNF and metabolic disease: It is important to mention that there may be other potential markers towards neurodegenerative or metabolic diseases during aging, some of them have still unveiled roles, nevertheless BDNF may play a role as one of the possible genetic markers that could help us to identify susceptible individuals to pathologies associated with aging, since if these people are identified on time it would be possible to take actions at least to delay the progress of these diseases.