The protein products of the some genes are of primary importance in inflammation and immune response, namely colony-stimulating factor receptors, TNF receptor superfamily members 1A and 1B, TLR5 and TLR8 receptors that induce the proinflammatory cytokine, and IL18 cytokine receptor that participates in innate immunity response and is a critical molecule in atherosclerosis-connected inflammation [35]. The gene discussed is TLR5; the disease is atherosclerosis.