The formation of PEBP1–ALOX15 complexes may mediate oxidative injury and asthma-related airway inflammation.25 Interestingly, P. aeruginosa can release ALOX15 to induce ferroptosis in bronchial epithelial cells, indicating that pathogen-mediated ALOX15 production mediates host cell death and infection.190. The gene discussed is ALOX15; the disease is asthma.