MYC and cancer: Notably, RNAseq analyses revealed that MYC, the well-established oncogenic driver and essential cancer-dependency of MYCamp-G3-MB10, was within the 479 shared significantly downregulated genes between the two MYCamp-G3-MB lines and it ranks 579th in HDMB03 and 211th in D458 among all detected genes according to the fold change of gene downregulation.