In all samples, TP-0903 inhibited cell viability at IC50 values < 100 nM (median, 35 nM; range, 21–67 nM); in AML samples with FLT3-ITD mutations, gilteritinib was less effective with all but 1 IC50 value > 100 nM (median, 263 nM; range, 93–1307 nM) (Figure 5E). This evidence concerns the gene FLT3 and acute myeloid leukemia.