These antigens are overexpressed by tumor cells but also shared with normal tissue (eg, carcinoembryonic antigen (CEA), epithelial cell adhesion molecule (Ep-CAM), mucin-1 (MUC-1), melanoma antigen recognized by T cells-1 (MART-1/Melan-A), glycoprotein 100 (gp100), and tyrosinase (Tyr)). This evidence concerns the gene CEACAM5 and neoplasm.