CDH1 and reading: Mining TCGA database using analyzing tools from starBase database (http://starbase.sysu.edu.cn/),we found that the expression of CDH1 (E-cadherin), a well-accepted marker negatively associated with EMT and metastasis, is positively correlated with the expression of HDAC2 in CRC(including 471 COAD samples and 167 READ samples, Fig. 1f and g).