MIR22HG and cancer: Various mechanisms have been implicated in the MIR22HG-mediated regulation of cancer progression; for example, MIR22HG has been reported to function as a competitive endogenous RNA (ceRNA) (Fig. 1a), be involved in signaling pathways (Fig. 1b), interact with proteins (Fig. 1c) and interplay with miRNAs as a host gene (Fig. 1d).