The Role of Tissue Factor in Cancer was enriched in > 50% of samples only at stage I. Four of the seven proteins driving enrichment of The Role of Tissue Factor in Cancer are also candidate biomarkers: RAC-gamma serine/threonine-protein kinase (AKT3), Cofilin1 and 2 (CFL1, CFL2), and integrin beta 3 (ITGB3). This evidence concerns the gene CFL2 and cancer.