Altogether these previous investigations proved the therapeutic value of Treg to resolve established allergen-induced pulmonary inflammation (eosinophilia, Th2 infiltration, IL-5, IL-13, and TGF-β, but also prevent the progression of airway remodeling, and reduce mucus hypersecretion and peribronchial collagen deposition [99, 100]. This evidence concerns the gene TGFB1 and Increased total eosinophil count.