Compared with the patients in higher tertiles, those in lower tertiles (lower FD ratios) exhibited lower HDL-C (p < 0.0001) and higher WC, BMI, body fat, SBP, DBP, FPG, TCH, TG, LDL-C, MetS, insulin, HOMA-IR, and abnormal liver function (p = 0.0353 for TCH; p = 0.0022 for LDL-C; p < 0.0001 for the others). The gene discussed is INS; the disease is metabolic syndrome.