Both the gastrin antagonist netazepide [128] and the somatostatin analogue octreotide [44] make gastric ECL cell NETs disappear, and it would be interesting to treat gastric carcinomas expressing both somatostatin 2 and gastrin receptors with a combination of these two agents, each having very little side effects. The gene discussed is CCKBR; the disease is gastric carcinoma.