Similarly, no differences in Rad51 mRNA levels were observed between non-treated and MK-2206-treated SK-LMS-1 leiomyosarcoma and RD rhabdomyosarcoma cell lines, thereby revealing that inhibition of AKT-signaling has no impact on Rad51 transcription in GIST and STS (Figure S9). Here, AKT1 is linked to gastrointestinal stromal tumor.