IL4 and Alzheimer disease: In an in vivo model of AD on BALB/cAJcl mice, the oral administration of an exopolysaccharide (EPS) produced by Lactobacillus paracasei reduced ear swelling, produced a repression of ear interleukin-4 (T helper (Th) 2 cytokine) mRNA and decreased serum immunoglobulin E levels.