ACHE and prostate carcinoma: A number of studies have reported on the biomedical efficacy of Rubi Fructus, such as its anti-inflammatory effects [12], antioxidative effects [10], improvements in visual sensitivity [28], acetylcholinesterase inhibitory activity [29], improvements in diabetic osteoporosis by simultaneous regulation of osteoblasts and osteoclasts [30], hepatoprotective effects [31], anti-fatigue effects [32], increased hypocholesterolemic activity [33], chemopreventive effects in prostate cancer [34], increased anti-anaphylactic activity [35], and enhanced spermatogenesis [36].