Given these findings, we confirmed that NS powder was effective for reducing fat weight and improving lipid profiles through promoting PPAR-α expression; improving insulin sensitivity through promoting PPAR-γ expression; reducing inflammation through reducing TNF-α expression, besides regulating blood glucose and alleviating glucose intolerance through promoting GLUT4 expression, which is also known to be inhibited by TNF-α. The gene discussed is SLC2A4; the disease is Glucose intolerance.