CD4 and tuberculosis: Recently, Esteves et al. [76] identified new potential markers to establish an analysis algorithm that allows discriminating between patients with active TB and latent TB by analyzing the expression of CD154 (CD40L) in central memory CD4 T lymphocytes (TCM) as the best candidate, since it has been observed that this population expands after activation with Mtb, contributing to CD27 and CD45RO expression in TCM.