As part of the clinical follow-up, Wiest et al. [53] described that patients with asthma have decreased lymphocyte B CD5+ and CD1d+CD5+ frequency, but an increase in cells B CD27+, suggesting that monitoring the expression of CD5, CD1d and CD27 in B cell subpopulations is useful in the clinical follow-up of people with asthma. Here, CD27 is linked to asthma.