This syndrome is associated with the development of pleuropulmonary blastomas, cystic nephroma, rhabdomyosarcoma, and several endocrine neoplasms, including thyroid cancer, ovarian tumors, and ACTH-secreting pituitary blastoma [90,91], thereby suggesting a pathogenic role for microRNAs in ACTHomas. The gene discussed is POMC; the disease is thyroid gland carcinoma.