CRP and psychiatric disorder: Aside from clinical symptoms of severity, CRP > 200 mg/L or CRP = 50–200 mg/L + allergic to penicillin or CRP = 50–200 mg/L + mandibular molar infection + psychiatric disorder or CRP < 50 mg/L + immunodepression increase the risk to have adverse evolution during hospitalization of more than 25% (Figure 2).