In the absence of reliable clinical examination, we identified measurable and objective criteria that increase the risk from 25% to 33% to have complications during hospitalization, they are CRP level higher than 200 mg/L, CRP level between 50 and 200 mg/L and allergic to penicillin, CRP level between 50 and 200 mg/L, mandibular molar infection and psychiatric disorder and CRP < 50 mg/L or CRP level unknown and immunodepression. The gene discussed is CRP; the disease is psychiatric disorder.