SCD and breast cancer: Fatty acids were shown to induce NF-κB activity through the activation of TLR4 signaling [124]; fatty acid-binding protein 5 (FABP5) increased tumorigenesis of breast cancer cells possibly through the induction of NF-κB [125]; and the products of SCD1 were shown to be essential to NF-κB activity in ovarian CSCs [126].