A family history could open possibilities for early primary and secondary prevention of these diseases and their monogenetic disease equivalents (e.g., long QT syndrome, breast cancer caused by BRCA1/2 mutations, Maturity onset diabetes of the young (MODY) subtypes) and could also be used to find, inform and treat unaffected family members pre-symptomatically [9]. Here, BRCA1 is linked to breast carcinoma.