Several detection techniques for EGFR mutations in plasma-derived cfDNA have been developed as non-invasive alternatives to tumor EGFR genotyping [5], such as cobas® EGFR mutation test v2, BEAMing-PCR (BEAM refers to Beads, Emulsions, Amplification and Magnetics) PCR [6], ARMS-PCR (ARMS refers to Amplification Refractory Mutation System), and ddPCRTM (dd refers to Droplet Digital). Here, EGFR is linked to neoplasm.